The so-called echo-sclerotherapy of the saphena vein is based on the same principle as the above mentioned sclerotherapy of branch varicosities. However, it is always performed by means of ultrasonic control because the diseased main vein often cannot be located through the skin. The vein specialist will always use foamed sclerosing agent, which reaches better adherence in large vessels. This technique is also painless and not associated with restrictions in every-day activities. Only intensive physical exertion should be avoided at least until the check-up after a few days.